Amyotrophic Lateral Sclerosis, or ALS, is a disease in which certain nerve cells in the brain and spinal cord slowly die. These nerve cells are called motor neurons, and they control the muscles that allow you to move the parts of your body. ALS is also called Lou Gehrig’s disease. People who have ALS gradually become more disabled. How quickly the disease gets worse is different for everyone. Some people live with ALS for several years. But over time, ALS makes it hard to walk, speak, eat, swallow, and breathe. These problems can lead to injury, illness, and eventually death. In most cases, death will occur within 3 to 5 years after symptoms begin, although some people do live for many years, even decades. Doctors don’t know what causes ALS. In about 1 case out of 10, it runs in families. This means that 9 times out of 10, with ALS doesn’t have a family member with the disease.
At the onset of ALS the symptoms may be so slight that they are frequently overlooked. With regard to the appearance of symptoms and the progression of the illness, the course of the disease may include the following  :
There is no cure for ALS, but treatment can help you stay strong and independent for as long as possible. Traditional treatment options include:
A medicine called riluzole (Rilutek) may prolong survival by about 2 months. But it doesn’t improve symptoms or quality of life in ways that people with ALS, their caregivers, or their doctors have been able to notice. Most people tolerate riluzole very well, but it can cause side effects, including nausea, vomiting, weakness, dizziness, and coughing. 
Stem cells have emerged as a major tool for research into the causes of ALS, and in the search for new management strategies. In the past decade, great accomplishments have been made in the development and clinical translation of stem cell therapies for ALS. These therapies are considered experimental. Mesenchymal stem cells (MSCs) stand out as cells that appear capable of protecting motor neurons (MNs), differentiating into multiple neural cell types, modulating immune cell roles, and reducing central nervous system (CNS) inflammation. The success of MSCs in delaying disease onset, improving motor function, and increasing survival in preclinical models of ALS has resulted in multiple clinical trials of MSC therapy in patients with ALS. These trials have established the safety of MSC delivery for CNS applications, opening the door for larger late-phase trials to better understand the effectiveness of MSC therapy in humans. The development of a therapy that can support or restore MN function and attenuate toxicity in the spinal cord provides the most comprehensive approach for managing ALS. 
If you have ALS and are interested in learning about stem cells from experts, then contact us.
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Actual results may vary. The statements are not intended to imply that the results would be the same or similar for each patient. Each patient is unique and no particular result or outcome can be predicted or guaranteed. The statements in this website have not been evaluated by the Food and Drug Administration. Some of these procedures may be considered experimental.
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